Indications
Relieves Abdominal Cramps and Spasms: Highly effective in treating severe, gripping pain in the stomach and intestines caused by sudden, involuntary muscle contractions (spasms).
Useful in Dysmenorrhea (Menstrual Cramps): Specifically indicated for women suffering from debilitating period pain. It rapidly relaxes the cramping uterine muscles and reduces the inflammatory pain associated with menstruation.
Effective in Renal Colic: Provides critical relief for the sharp, radiating pain caused by kidney stones passing through the urinary tract by relaxing the smooth muscles of the ureter.
Used in GI Spasm Disorders: A trusted treatment for managing painful gastrointestinal conditions, including Irritable Bowel Syndrome (IBS), severe indigestion, and intestinal colic.
Combines Muscle Relaxation and Pain Relief: Addresses pain from two different angles simultaneously, making it much more effective for spasmodic pain than standard painkillers.
Useful in Dysmenorrhea (Menstrual Cramps): Specifically indicated for women suffering from debilitating period pain. It rapidly relaxes the cramping uterine muscles and reduces the inflammatory pain associated with menstruation.
Effective in Renal Colic: Provides critical relief for the sharp, radiating pain caused by kidney stones passing through the urinary tract by relaxing the smooth muscles of the ureter.
Used in GI Spasm Disorders: A trusted treatment for managing painful gastrointestinal conditions, including Irritable Bowel Syndrome (IBS), severe indigestion, and intestinal colic.
Combines Muscle Relaxation and Pain Relief: Addresses pain from two different angles simultaneously, making it much more effective for spasmodic pain than standard painkillers.
Uses
Targeted Spasm Relief (Drotaverine): Drotaverine is a powerful antispasmodic agent. It works directly on the smooth muscles of the abdomen, uterus, and urinary tract, quickly relaxing the tight, knotted muscles that are causing the severe cramping sensation.
Potent Pain Blockade (Mefenamic Acid): Mefenamic Acid is a Non-Steroidal Anti-Inflammatory Drug (NSAID). It actively blocks the body’s production of prostaglandins—the chemical messengers responsible for triggering inflammation, swelling, and sharp pain.
Dual-Action Synergy: While Drotaverine stops the physical muscle spasm, Mefenamic Acid numbs the resulting pain and inflammation, providing comprehensive and rapid relief.
Biliary Colic Management: Efficiently manages sharp pain originating from the gallbladder or bile ducts (often related to gallstones).
Restores Comfort and Mobility: By quickly addressing both the root cause (the spasm) and the symptom (the pain), it allows patients to resume their daily activities comfortably.
Potent Pain Blockade (Mefenamic Acid): Mefenamic Acid is a Non-Steroidal Anti-Inflammatory Drug (NSAID). It actively blocks the body’s production of prostaglandins—the chemical messengers responsible for triggering inflammation, swelling, and sharp pain.
Dual-Action Synergy: While Drotaverine stops the physical muscle spasm, Mefenamic Acid numbs the resulting pain and inflammation, providing comprehensive and rapid relief.
Biliary Colic Management: Efficiently manages sharp pain originating from the gallbladder or bile ducts (often related to gallstones).
Restores Comfort and Mobility: By quickly addressing both the root cause (the spasm) and the symptom (the pain), it allows patients to resume their daily activities comfortably.
Dosage & Storage Title
Dosage Guidelines: Always follow the exact dose prescribed by your doctor. The dosage is typically based on the severity of your spasms and pain.
Adult Dose: Usually one tablet taken two to three times a day during an acute pain episode.
Short-Term Therapy: This medication is generally prescribed for short-term use (a few days) to manage acute flare-ups of pain, rather than as a continuous daily medication.
Storage Temperature: Store the tablets in a cool, dry place at room temperature (below 30°C).
Moisture Protection: Keep the tablets sealed in their original blister pack until you are ready to take them to protect them from light and humidity.
Adult Dose: Usually one tablet taken two to three times a day during an acute pain episode.
Short-Term Therapy: This medication is generally prescribed for short-term use (a few days) to manage acute flare-ups of pain, rather than as a continuous daily medication.
Storage Temperature: Store the tablets in a cool, dry place at room temperature (below 30°C).
Moisture Protection: Keep the tablets sealed in their original blister pack until you are ready to take them to protect them from light and humidity.
Directions For Use Title
Oral Administration: Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet.
Take With Food: Because this medicine contains an NSAID (Mefenamic Acid), it is highly recommended to take it with or immediately after a heavy meal. Taking it on an empty stomach increases the risk of heartburn and stomach irritation.
Do Not Exceed the Dose: Never take more tablets than your doctor has prescribed, even if the pain is severe, to avoid unnecessary stress on your stomach and liver.
Take With Food: Because this medicine contains an NSAID (Mefenamic Acid), it is highly recommended to take it with or immediately after a heavy meal. Taking it on an empty stomach increases the risk of heartburn and stomach irritation.
Do Not Exceed the Dose: Never take more tablets than your doctor has prescribed, even if the pain is severe, to avoid unnecessary stress on your stomach and liver.
Precautions
Avoid Alcohol: Strictly avoid consuming alcohol while taking DONISPAS. Mixing alcohol with Mefenamic Acid greatly increases the risk of severe stomach bleeding and liver damage.
Allergy History: Inform your doctor if you have asthma, or if you have ever had a severe allergic reaction (like hives or breathing difficulty) after taking Aspirin, Ibuprofen, or other NSAIDs.
Pregnancy and Breastfeeding: This combination is generally not recommended during pregnancy (especially in the third trimester) or while breastfeeding unless specifically prescribed by a gynecologist.
Kidney and Liver Health: Patients with pre-existing kidney or liver diseases must consult their doctor before using this medicine, as dose adjustments may be required.
Driving Warning: Because this medicine can occasionally cause dizziness or drowsiness, avoid driving or operating heavy machinery until you know how it affects you.
Allergy History: Inform your doctor if you have asthma, or if you have ever had a severe allergic reaction (like hives or breathing difficulty) after taking Aspirin, Ibuprofen, or other NSAIDs.
Pregnancy and Breastfeeding: This combination is generally not recommended during pregnancy (especially in the third trimester) or while breastfeeding unless specifically prescribed by a gynecologist.
Kidney and Liver Health: Patients with pre-existing kidney or liver diseases must consult their doctor before using this medicine, as dose adjustments may be required.
Driving Warning: Because this medicine can occasionally cause dizziness or drowsiness, avoid driving or operating heavy machinery until you know how it affects you.
Side Effects
Dizziness
Nausea
Dry mouth
Gastric discomfort
Skin rashes
Nausea
Dry mouth
Gastric discomfort
Skin rashes
Medical Disclaimer
Informational Only: The information provided is for educational and informational purposes only and is not intended as medical advice.
Professional Guidance: Always consult a healthcare professional for medical advice, diagnosis, or treatment.
No Claims: Agnes Life Sciences does not claim that any of its products can diagnose, treat, cure, or prevent any disease.
Professional Guidance: Always consult a healthcare professional for medical advice, diagnosis, or treatment.
No Claims: Agnes Life Sciences does not claim that any of its products can diagnose, treat, cure, or prevent any disease.
Indications
Relieves Abdominal Cramps and Spasms: Highly effective in treating severe, gripping pain in the stomach and intestines caused by sudden, involuntary muscle contractions (spasms).
Useful in Dysmenorrhea (Menstrual Cramps): Specifically indicated for women suffering from debilitating period pain. It rapidly relaxes the cramping uterine muscles and reduces the inflammatory pain associated with menstruation.
Effective in Renal Colic: Provides critical relief for the sharp, radiating pain caused by kidney stones passing through the urinary tract by relaxing the smooth muscles of the ureter.
Used in GI Spasm Disorders: A trusted treatment for managing painful gastrointestinal conditions, including Irritable Bowel Syndrome (IBS), severe indigestion, and intestinal colic.
Combines Muscle Relaxation and Pain Relief: Addresses pain from two different angles simultaneously, making it much more effective for spasmodic pain than standard painkillers.
Useful in Dysmenorrhea (Menstrual Cramps): Specifically indicated for women suffering from debilitating period pain. It rapidly relaxes the cramping uterine muscles and reduces the inflammatory pain associated with menstruation.
Effective in Renal Colic: Provides critical relief for the sharp, radiating pain caused by kidney stones passing through the urinary tract by relaxing the smooth muscles of the ureter.
Used in GI Spasm Disorders: A trusted treatment for managing painful gastrointestinal conditions, including Irritable Bowel Syndrome (IBS), severe indigestion, and intestinal colic.
Combines Muscle Relaxation and Pain Relief: Addresses pain from two different angles simultaneously, making it much more effective for spasmodic pain than standard painkillers.
Uses
Targeted Spasm Relief (Drotaverine): Drotaverine is a powerful antispasmodic agent. It works directly on the smooth muscles of the abdomen, uterus, and urinary tract, quickly relaxing the tight, knotted muscles that are causing the severe cramping sensation.
Potent Pain Blockade (Mefenamic Acid): Mefenamic Acid is a Non-Steroidal Anti-Inflammatory Drug (NSAID). It actively blocks the body’s production of prostaglandins—the chemical messengers responsible for triggering inflammation, swelling, and sharp pain.
Dual-Action Synergy: While Drotaverine stops the physical muscle spasm, Mefenamic Acid numbs the resulting pain and inflammation, providing comprehensive and rapid relief.
Biliary Colic Management: Efficiently manages sharp pain originating from the gallbladder or bile ducts (often related to gallstones).
Restores Comfort and Mobility: By quickly addressing both the root cause (the spasm) and the symptom (the pain), it allows patients to resume their daily activities comfortably.
Potent Pain Blockade (Mefenamic Acid): Mefenamic Acid is a Non-Steroidal Anti-Inflammatory Drug (NSAID). It actively blocks the body’s production of prostaglandins—the chemical messengers responsible for triggering inflammation, swelling, and sharp pain.
Dual-Action Synergy: While Drotaverine stops the physical muscle spasm, Mefenamic Acid numbs the resulting pain and inflammation, providing comprehensive and rapid relief.
Biliary Colic Management: Efficiently manages sharp pain originating from the gallbladder or bile ducts (often related to gallstones).
Restores Comfort and Mobility: By quickly addressing both the root cause (the spasm) and the symptom (the pain), it allows patients to resume their daily activities comfortably.
Dosage & Storage
Dosage Guidelines: Always follow the exact dose prescribed by your doctor. The dosage is typically based on the severity of your spasms and pain.
Adult Dose: Usually one tablet taken two to three times a day during an acute pain episode.
Short-Term Therapy: This medication is generally prescribed for short-term use (a few days) to manage acute flare-ups of pain, rather than as a continuous daily medication.
Storage Temperature: Store the tablets in a cool, dry place at room temperature (below 30°C).
Moisture Protection: Keep the tablets sealed in their original blister pack until you are ready to take them to protect them from light and humidity.
Adult Dose: Usually one tablet taken two to three times a day during an acute pain episode.
Short-Term Therapy: This medication is generally prescribed for short-term use (a few days) to manage acute flare-ups of pain, rather than as a continuous daily medication.
Storage Temperature: Store the tablets in a cool, dry place at room temperature (below 30°C).
Moisture Protection: Keep the tablets sealed in their original blister pack until you are ready to take them to protect them from light and humidity.
Directions For Use
Oral Administration: Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet.
Take With Food: Because this medicine contains an NSAID (Mefenamic Acid), it is highly recommended to take it with or immediately after a heavy meal. Taking it on an empty stomach increases the risk of heartburn and stomach irritation.
Do Not Exceed the Dose: Never take more tablets than your doctor has prescribed, even if the pain is severe, to avoid unnecessary stress on your stomach and liver.
Take With Food: Because this medicine contains an NSAID (Mefenamic Acid), it is highly recommended to take it with or immediately after a heavy meal. Taking it on an empty stomach increases the risk of heartburn and stomach irritation.
Do Not Exceed the Dose: Never take more tablets than your doctor has prescribed, even if the pain is severe, to avoid unnecessary stress on your stomach and liver.
Precautions
Avoid Alcohol: Strictly avoid consuming alcohol while taking DONISPAS. Mixing alcohol with Mefenamic Acid greatly increases the risk of severe stomach bleeding and liver damage.
Allergy History: Inform your doctor if you have asthma, or if you have ever had a severe allergic reaction (like hives or breathing difficulty) after taking Aspirin, Ibuprofen, or other NSAIDs.
Pregnancy and Breastfeeding: This combination is generally not recommended during pregnancy (especially in the third trimester) or while breastfeeding unless specifically prescribed by a gynecologist.
Kidney and Liver Health: Patients with pre-existing kidney or liver diseases must consult their doctor before using this medicine, as dose adjustments may be required.
Driving Warning: Because this medicine can occasionally cause dizziness or drowsiness, avoid driving or operating heavy machinery until you know how it affects you.
Allergy History: Inform your doctor if you have asthma, or if you have ever had a severe allergic reaction (like hives or breathing difficulty) after taking Aspirin, Ibuprofen, or other NSAIDs.
Pregnancy and Breastfeeding: This combination is generally not recommended during pregnancy (especially in the third trimester) or while breastfeeding unless specifically prescribed by a gynecologist.
Kidney and Liver Health: Patients with pre-existing kidney or liver diseases must consult their doctor before using this medicine, as dose adjustments may be required.
Driving Warning: Because this medicine can occasionally cause dizziness or drowsiness, avoid driving or operating heavy machinery until you know how it affects you.
Side Effects
Dizziness
Nausea
Dry mouth
Gastric discomfort
Skin rashes
Nausea
Dry mouth
Gastric discomfort
Skin rashes
Medical Disclaimer
Informational Only: The information provided is for educational and informational purposes only and is not intended as medical advice.
Professional Guidance: Always consult a healthcare professional for medical advice, diagnosis, or treatment.
No Claims: Agnes Life Sciences does not claim that any of its products can diagnose, treat, cure, or prevent any disease.
Professional Guidance: Always consult a healthcare professional for medical advice, diagnosis, or treatment.
No Claims: Agnes Life Sciences does not claim that any of its products can diagnose, treat, cure, or prevent any disease.







