PANTAG-LSR
COMPOSITION
Pantoprazole 40mg + Levosulpiride 75mg
Category
Capsules
| Packing |
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ENQUIRY
Indications
PANTAG-LSR is clinically indicated for the management of various upper gastrointestinal and acid-related conditions:
Gastroesophageal Reflux Disease (GERD): Specifically indicated for patients suffering from persistent acid backflow that has not responded to standard, single-agent antacid treatments.
Acid Peptic Disorders: Management of chronic conditions characterized by excessive gastric acid production and distressing upper abdominal pain.
Functional Dyspepsia: Relief from persistent indigestion, early satiety (feeling full quickly), and a constant sensation of stomach “heaviness” that has no obvious structural or visible cause.
Gastritis: Clinical treatment of the acute or chronic inflammation of the stomach lining, often exacerbated by chemical acid irritation or dietary triggers.
Peptic Ulcer: Used to promote the accelerated healing of sores in the lining of the stomach or the duodenum (the first part of the small intestine) by reducing corrosive acid exposure.
Reflux Esophagitis: Healing the mucosal damage and inflammation of the esophagus caused by the chronic upward movement of stomach acid.
Gastroesophageal Reflux Disease (GERD): Specifically indicated for patients suffering from persistent acid backflow that has not responded to standard, single-agent antacid treatments.
Acid Peptic Disorders: Management of chronic conditions characterized by excessive gastric acid production and distressing upper abdominal pain.
Functional Dyspepsia: Relief from persistent indigestion, early satiety (feeling full quickly), and a constant sensation of stomach “heaviness” that has no obvious structural or visible cause.
Gastritis: Clinical treatment of the acute or chronic inflammation of the stomach lining, often exacerbated by chemical acid irritation or dietary triggers.
Peptic Ulcer: Used to promote the accelerated healing of sores in the lining of the stomach or the duodenum (the first part of the small intestine) by reducing corrosive acid exposure.
Reflux Esophagitis: Healing the mucosal damage and inflammation of the esophagus caused by the chronic upward movement of stomach acid.
Uses
The clinical utility of PANTAG-LSR centers on its ability to synchronize the digestive system while neutralizing chemical triggers of pain:
Effective in GERD with Gastroparesis: Pantoprazole reduces the total volume of acid, while Levosulpiride treats “gastroparesis” or slow stomach emptying, which is a primary mechanical cause of reflux symptoms.
Treats Indigestion with Bloating: Levosulpiride acts as a dopamine D2 antagonist on the upper digestive tract to increase the rhythmic movements of the stomach, allowing trapped gas and food to move downward efficiently.
Reduces Acid Secretion: Pantoprazole works by irreversibly inhibiting the ATPase enzyme system (the proton pumps) in the stomach lining, providing a profound reduction in acid production for up to 24 hours.
Improves Stomach Motility: It enhances the muscle tone of the lower esophageal sphincter (LES), which acts as a physical one-way barrier against the backflow of acid into the food pipe.
Helpful in Functional Dyspepsia: Effectively addresses the “bloated” feeling, post-prandial fullness, and loss of appetite associated with sluggish or dysfunctional digestion.
Correction of Dysmotility: By stimulating the myenteric plexus, it ensures that the waves of digestive contraction (peristalsis) are strong and coordinated.
Effective in GERD with Gastroparesis: Pantoprazole reduces the total volume of acid, while Levosulpiride treats “gastroparesis” or slow stomach emptying, which is a primary mechanical cause of reflux symptoms.
Treats Indigestion with Bloating: Levosulpiride acts as a dopamine D2 antagonist on the upper digestive tract to increase the rhythmic movements of the stomach, allowing trapped gas and food to move downward efficiently.
Reduces Acid Secretion: Pantoprazole works by irreversibly inhibiting the ATPase enzyme system (the proton pumps) in the stomach lining, providing a profound reduction in acid production for up to 24 hours.
Improves Stomach Motility: It enhances the muscle tone of the lower esophageal sphincter (LES), which acts as a physical one-way barrier against the backflow of acid into the food pipe.
Helpful in Functional Dyspepsia: Effectively addresses the “bloated” feeling, post-prandial fullness, and loss of appetite associated with sluggish or dysfunctional digestion.
Correction of Dysmotility: By stimulating the myenteric plexus, it ensures that the waves of digestive contraction (peristalsis) are strong and coordinated.
Dosage & Storage
Proper handling and adherence to the prescribed schedule are essential for the pharmacological stability of the sustained-release medication:
Adult Dosage: The common therapeutic dose is one capsule daily. Always take PANTAG-LSR in the exact dose directed by your physician based on the severity of your symptoms. Do not exceed the recommended dose to avoid potential hormonal or neurological side effects.
Storage Temperature: Store this drug at room temperature (ideally below 25°C), away from excessive moisture and direct heat sources.
Safety: Store in a secure, elevated location well out of the reach of children and domestic pets to prevent accidental ingestion.
Packaging Integrity: Keep the capsules in their original Alu-Alu or blister strip to protect the light-sensitive active ingredients from environmental degradation.
Adult Dosage: The common therapeutic dose is one capsule daily. Always take PANTAG-LSR in the exact dose directed by your physician based on the severity of your symptoms. Do not exceed the recommended dose to avoid potential hormonal or neurological side effects.
Storage Temperature: Store this drug at room temperature (ideally below 25°C), away from excessive moisture and direct heat sources.
Safety: Store in a secure, elevated location well out of the reach of children and domestic pets to prevent accidental ingestion.
Packaging Integrity: Keep the capsules in their original Alu-Alu or blister strip to protect the light-sensitive active ingredients from environmental degradation.
Directions For Use
To ensure that the gastro-resistant and sustained-release pellets work as intended and reach the small intestine intact, patients must follow these administration steps:
The “60-Minute” Rule: Take the capsule exactly 60 minutes before a meal to optimize its prokinetic effects and ensure acid pumps are inhibited before food arrives.
Timing: Take it once daily, ideally early in the morning upon waking, or as specifically directed by your healthcare provider.
Swallow Whole: Take the capsule whole with a full glass of water to facilitate its passage into the stomach.
Integrity of Pellets: Do not crush, break, or open the capsule. The medicine is contained in pellets specially coated to release at specific intervals throughout the day. Breaking the capsule destroys this mechanism, which can lead to severe stomach irritation or complete drug inactivation.
Hydration: Maintaining adequate fluid intake throughout the day supports the motility effects of the prokinetic component.
The “60-Minute” Rule: Take the capsule exactly 60 minutes before a meal to optimize its prokinetic effects and ensure acid pumps are inhibited before food arrives.
Timing: Take it once daily, ideally early in the morning upon waking, or as specifically directed by your healthcare provider.
Swallow Whole: Take the capsule whole with a full glass of water to facilitate its passage into the stomach.
Integrity of Pellets: Do not crush, break, or open the capsule. The medicine is contained in pellets specially coated to release at specific intervals throughout the day. Breaking the capsule destroys this mechanism, which can lead to severe stomach irritation or complete drug inactivation.
Hydration: Maintaining adequate fluid intake throughout the day supports the motility effects of the prokinetic component.
Precautions
Before beginning a course of PANTAG-LSR, the following clinical considerations should be evaluated by a medical expert:
Acidity Relief: This medication is designed to provide systemic relief from acidity and related dysmotility symptoms and is generally well-tolerated over a period of many hours.
Morning Routine: For the best pharmacokinetic results and consistent acid control, integrate the medication into your early morning routine, at least one hour before your first meal.
Symptom Monitoring: Inform your doctor immediately if you experience unusual symptoms such as watery diarrhea, persistent fever, or sharp, continuous stomach pain during therapy.
Course Completion: Complete the full course of the medication as advised by your physician, even if you feel better after a few days, to prevent a relapse of gastric symptoms.
Medical History: Inform your doctor if you have a history of heart rhythm issues, pituitary tumors, or epilepsy, as Levosulpiride may require extra caution in these cases.
Bone Health: Long-term use of PPIs like Pantoprazole may affect calcium absorption; discuss bone health and mineral supplementation with your doctor if you are on extended therapy.
Acidity Relief: This medication is designed to provide systemic relief from acidity and related dysmotility symptoms and is generally well-tolerated over a period of many hours.
Morning Routine: For the best pharmacokinetic results and consistent acid control, integrate the medication into your early morning routine, at least one hour before your first meal.
Symptom Monitoring: Inform your doctor immediately if you experience unusual symptoms such as watery diarrhea, persistent fever, or sharp, continuous stomach pain during therapy.
Course Completion: Complete the full course of the medication as advised by your physician, even if you feel better after a few days, to prevent a relapse of gastric symptoms.
Medical History: Inform your doctor if you have a history of heart rhythm issues, pituitary tumors, or epilepsy, as Levosulpiride may require extra caution in these cases.
Bone Health: Long-term use of PPIs like Pantoprazole may affect calcium absorption; discuss bone health and mineral supplementation with your doctor if you are on extended therapy.
Side Effects
Restlessness
Weight Gain
Tremors (Rare)
Increased Prolactin Levels
Drowsiness
Weight Gain
Tremors (Rare)
Increased Prolactin Levels
Drowsiness
Medical Disclaimer
The information provided is for educational and informational purposes only and is not intended as medical advice. Always consult a healthcare professional for medical advice, diagnosis, or treatment. Agnes Life Sciences does not claim that any of its products can diagnose, treat, cure, or prevent any disease. This medication is a prescription-only product and should only be used under the direct supervision of a licensed physician.
Indications
PANTAG-LSR is clinically indicated for the management of various upper gastrointestinal and acid-related conditions:
Gastroesophageal Reflux Disease (GERD): Specifically indicated for patients suffering from persistent acid backflow that has not responded to standard, single-agent antacid treatments.
Acid Peptic Disorders: Management of chronic conditions characterized by excessive gastric acid production and distressing upper abdominal pain.
Functional Dyspepsia: Relief from persistent indigestion, early satiety (feeling full quickly), and a constant sensation of stomach “heaviness” that has no obvious structural or visible cause.
Gastritis: Clinical treatment of the acute or chronic inflammation of the stomach lining, often exacerbated by chemical acid irritation or dietary triggers.
Peptic Ulcer: Used to promote the accelerated healing of sores in the lining of the stomach or the duodenum (the first part of the small intestine) by reducing corrosive acid exposure.
Reflux Esophagitis: Healing the mucosal damage and inflammation of the esophagus caused by the chronic upward movement of stomach acid.
Gastroesophageal Reflux Disease (GERD): Specifically indicated for patients suffering from persistent acid backflow that has not responded to standard, single-agent antacid treatments.
Acid Peptic Disorders: Management of chronic conditions characterized by excessive gastric acid production and distressing upper abdominal pain.
Functional Dyspepsia: Relief from persistent indigestion, early satiety (feeling full quickly), and a constant sensation of stomach “heaviness” that has no obvious structural or visible cause.
Gastritis: Clinical treatment of the acute or chronic inflammation of the stomach lining, often exacerbated by chemical acid irritation or dietary triggers.
Peptic Ulcer: Used to promote the accelerated healing of sores in the lining of the stomach or the duodenum (the first part of the small intestine) by reducing corrosive acid exposure.
Reflux Esophagitis: Healing the mucosal damage and inflammation of the esophagus caused by the chronic upward movement of stomach acid.
Uses
The clinical utility of PANTAG-LSR centers on its ability to synchronize the digestive system while neutralizing chemical triggers of pain:
Effective in GERD with Gastroparesis: Pantoprazole reduces the total volume of acid, while Levosulpiride treats “gastroparesis” or slow stomach emptying, which is a primary mechanical cause of reflux symptoms.
Treats Indigestion with Bloating: Levosulpiride acts as a dopamine D2 antagonist on the upper digestive tract to increase the rhythmic movements of the stomach, allowing trapped gas and food to move downward efficiently.
Reduces Acid Secretion: Pantoprazole works by irreversibly inhibiting the ATPase enzyme system (the proton pumps) in the stomach lining, providing a profound reduction in acid production for up to 24 hours.
Improves Stomach Motility: It enhances the muscle tone of the lower esophageal sphincter (LES), which acts as a physical one-way barrier against the backflow of acid into the food pipe.
Helpful in Functional Dyspepsia: Effectively addresses the “bloated” feeling, post-prandial fullness, and loss of appetite associated with sluggish or dysfunctional digestion.
Correction of Dysmotility: By stimulating the myenteric plexus, it ensures that the waves of digestive contraction (peristalsis) are strong and coordinated.
Effective in GERD with Gastroparesis: Pantoprazole reduces the total volume of acid, while Levosulpiride treats “gastroparesis” or slow stomach emptying, which is a primary mechanical cause of reflux symptoms.
Treats Indigestion with Bloating: Levosulpiride acts as a dopamine D2 antagonist on the upper digestive tract to increase the rhythmic movements of the stomach, allowing trapped gas and food to move downward efficiently.
Reduces Acid Secretion: Pantoprazole works by irreversibly inhibiting the ATPase enzyme system (the proton pumps) in the stomach lining, providing a profound reduction in acid production for up to 24 hours.
Improves Stomach Motility: It enhances the muscle tone of the lower esophageal sphincter (LES), which acts as a physical one-way barrier against the backflow of acid into the food pipe.
Helpful in Functional Dyspepsia: Effectively addresses the “bloated” feeling, post-prandial fullness, and loss of appetite associated with sluggish or dysfunctional digestion.
Correction of Dysmotility: By stimulating the myenteric plexus, it ensures that the waves of digestive contraction (peristalsis) are strong and coordinated.
Dosage & Storage
Proper handling and adherence to the prescribed schedule are essential for the pharmacological stability of the sustained-release medication:
Adult Dosage: The common therapeutic dose is one capsule daily. Always take PANTAG-LSR in the exact dose directed by your physician based on the severity of your symptoms. Do not exceed the recommended dose to avoid potential hormonal or neurological side effects.
Storage Temperature: Store this drug at room temperature (ideally below 25°C), away from excessive moisture and direct heat sources.
Safety: Store in a secure, elevated location well out of the reach of children and domestic pets to prevent accidental ingestion.
Packaging Integrity: Keep the capsules in their original Alu-Alu or blister strip to protect the light-sensitive active ingredients from environmental degradation.
Adult Dosage: The common therapeutic dose is one capsule daily. Always take PANTAG-LSR in the exact dose directed by your physician based on the severity of your symptoms. Do not exceed the recommended dose to avoid potential hormonal or neurological side effects.
Storage Temperature: Store this drug at room temperature (ideally below 25°C), away from excessive moisture and direct heat sources.
Safety: Store in a secure, elevated location well out of the reach of children and domestic pets to prevent accidental ingestion.
Packaging Integrity: Keep the capsules in their original Alu-Alu or blister strip to protect the light-sensitive active ingredients from environmental degradation.
Directions For Use
To ensure that the gastro-resistant and sustained-release pellets work as intended and reach the small intestine intact, patients must follow these administration steps:
The “60-Minute” Rule: Take the capsule exactly 60 minutes before a meal to optimize its prokinetic effects and ensure acid pumps are inhibited before food arrives.
Timing: Take it once daily, ideally early in the morning upon waking, or as specifically directed by your healthcare provider.
Swallow Whole: Take the capsule whole with a full glass of water to facilitate its passage into the stomach.
Integrity of Pellets: Do not crush, break, or open the capsule. The medicine is contained in pellets specially coated to release at specific intervals throughout the day. Breaking the capsule destroys this mechanism, which can lead to severe stomach irritation or complete drug inactivation.
Hydration: Maintaining adequate fluid intake throughout the day supports the motility effects of the prokinetic component.
The “60-Minute” Rule: Take the capsule exactly 60 minutes before a meal to optimize its prokinetic effects and ensure acid pumps are inhibited before food arrives.
Timing: Take it once daily, ideally early in the morning upon waking, or as specifically directed by your healthcare provider.
Swallow Whole: Take the capsule whole with a full glass of water to facilitate its passage into the stomach.
Integrity of Pellets: Do not crush, break, or open the capsule. The medicine is contained in pellets specially coated to release at specific intervals throughout the day. Breaking the capsule destroys this mechanism, which can lead to severe stomach irritation or complete drug inactivation.
Hydration: Maintaining adequate fluid intake throughout the day supports the motility effects of the prokinetic component.
Precautions
Before beginning a course of PANTAG-LSR, the following clinical considerations should be evaluated by a medical expert:
Acidity Relief: This medication is designed to provide systemic relief from acidity and related dysmotility symptoms and is generally well-tolerated over a period of many hours.
Morning Routine: For the best pharmacokinetic results and consistent acid control, integrate the medication into your early morning routine, at least one hour before your first meal.
Symptom Monitoring: Inform your doctor immediately if you experience unusual symptoms such as watery diarrhea, persistent fever, or sharp, continuous stomach pain during therapy.
Course Completion: Complete the full course of the medication as advised by your physician, even if you feel better after a few days, to prevent a relapse of gastric symptoms.
Medical History: Inform your doctor if you have a history of heart rhythm issues, pituitary tumors, or epilepsy, as Levosulpiride may require extra caution in these cases.
Bone Health: Long-term use of PPIs like Pantoprazole may affect calcium absorption; discuss bone health and mineral supplementation with your doctor if you are on extended therapy.
Acidity Relief: This medication is designed to provide systemic relief from acidity and related dysmotility symptoms and is generally well-tolerated over a period of many hours.
Morning Routine: For the best pharmacokinetic results and consistent acid control, integrate the medication into your early morning routine, at least one hour before your first meal.
Symptom Monitoring: Inform your doctor immediately if you experience unusual symptoms such as watery diarrhea, persistent fever, or sharp, continuous stomach pain during therapy.
Course Completion: Complete the full course of the medication as advised by your physician, even if you feel better after a few days, to prevent a relapse of gastric symptoms.
Medical History: Inform your doctor if you have a history of heart rhythm issues, pituitary tumors, or epilepsy, as Levosulpiride may require extra caution in these cases.
Bone Health: Long-term use of PPIs like Pantoprazole may affect calcium absorption; discuss bone health and mineral supplementation with your doctor if you are on extended therapy.
Side Effects
Restlessness
Weight Gain
Tremors (Rare)
Increased Prolactin Levels
Drowsiness
Weight Gain
Tremors (Rare)
Increased Prolactin Levels
Drowsiness
Medical Disclaimer
The information provided is for educational and informational purposes only and is not intended as medical advice. Always consult a healthcare professional for medical advice, diagnosis, or treatment. Agnes Life Sciences does not claim that any of its products can diagnose, treat, cure, or prevent any disease. This medication is a prescription-only product and should only be used under the direct supervision of a licensed physician.






